Prophylactic misuse and recommended use of non-steroidal anti-inflammatory drugs by athletes

From the article:

Athletes who regularly take NSAIDs before exercise may have reduced tissue adaptation to prevailing loads potentially predisposing them to future injury.

Second, prolonged prophylactic use of NSAIDs has the potential to reduce the rate of matrix production and subsequent tissue repair following microscopic or macroscopic injury.

This has been shown most convincingly following fracture where prolonged NSAID use delayed healing, but NSAIDs also delay healing of acute ligament, muscle and tendon injuries.

http://bjsm.bmj.com/cgi/content/full/43/8/548